Z16Header code — not billable
Resistance to antimicrobial drugs
- Chapter
- 21. Factors influencing health status and contact with health services
- Category
- Z16
- Effective date
- October 1, 2026
Related codes in category Z16
Z16.1Resistance to beta lactam antibioticsZ16.10Resistance to unspecified beta lactam antibioticsYesZ16.11Resistance to penicillinsYesZ16.12Extended spectrum beta lactamase (ESBL) resistanceYesZ16.13Resistance to carbapenemYesZ16.19Resistance to other specified beta lactam antibioticsYesZ16.2Resistance to other antibioticsZ16.20Resistance to unspecified antibioticYesZ16.21Resistance to vancomycinYesZ16.22Resistance to vancomycin related antibioticsYesZ16.23Resistance to quinolones and fluoroquinolonesYesZ16.24Resistance to multiple antibioticsYes
Frequently asked questions
What is ICD-10 code Z16?
Z16 is an ICD-10-CM diagnosis code for Resistance to antimicrobial drugs.
Is Z16 a billable code?
No. Z16 is a category/header code, not billable on its own — use one of its more specific child codes instead.
What ICD-10-CM chapter is Z16 in?
Z16 falls under Chapter 21: Factors influencing health status and contact with health services.
When did Z16 become effective?
Z16 has been effective since October 1, 2026, per the CMS/CDC ICD-10-CM annual release.
What other codes are related to Z16?
Z16 belongs to category Z16, which includes 12 other codes — see the related codes list on this page.
ICD-10-CM data maintained by CDC/CMS (public domain). Always verify codes with authoritative sources before making coding or billing decisions.