R53Header code — not billable

Malaise and fatigue

Chapter
18. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Category
R53
Effective date
October 1, 2026

Related codes in category R53

R53.0Neoplastic (malignant) related fatigueYesR53.1WeaknessYesR53.2Functional quadriplegiaYesR53.8Other malaise and fatigueR53.81Other malaiseYesR53.82Chronic fatigue, unspecifiedYesR53.83Other fatigueYes

Frequently asked questions

What is ICD-10 code R53?

R53 is an ICD-10-CM diagnosis code for Malaise and fatigue.

Is R53 a billable code?

No. R53 is a category/header code, not billable on its own — use one of its more specific child codes instead.

What ICD-10-CM chapter is R53 in?

R53 falls under Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.

When did R53 become effective?

R53 has been effective since October 1, 2026, per the CMS/CDC ICD-10-CM annual release.

What other codes are related to R53?

R53 belongs to category R53, which includes 7 other codes — see the related codes list on this page.

ICD-10-CM data maintained by CDC/CMS (public domain). Always verify codes with authoritative sources before making coding or billing decisions.